Martin Pižl

Filed of research

1) transition metal complexes for DNA oxidation - substituted ligands, understanding the mechanism of DNA oxidation, tunning the redox and excited states properties 
2) CO₂ reduction and H₂ evolution catalysts - exploring the mechanisms and synhteses of new prototypes
3) complexes derived from vitamine B6 - modelling of enzymatic reaction centre

Research techniques

1) molecular spectroscopy (UV-Vis, FTIR, TRIR, 2DIR, T-2DIR, Raman)
2) electrochemistry and spectroelectrochemistry
3) quantum chemical calculations (Gaussian, Orca, Molcas etc.)

Fundings

1. GAČR PIF OUT (2023-2026): "Redox and photochemical properties of polypyridyl-based biosensors"
2. UCT Prague Rector’s Junior Grant (2022): “Photochemical and redox properties of Ru(II) polypyridyl biosensors: Experimental and theoretical study”

Publications

• Tolba, A.H.; El-Zohry, A.M.; Khan, J.I.; Svobodová, E.; Chudoba, J.; Klíma, J.; Lušpai, K.; Pižl, M.; Šturala, J.; Cibulka, R., Redox-innocent scandium(III) as the sole catalyst in visible light photooxidations. Nature Communication 2025, 16, 7851. DOI: 10.1038/s41467-025-63233-4
• Stitch, M; Pižl, M.; Lehane, N.; Greetham, G.M.; Hartl, F.; Towrie, M.; Quinn, S.J., Eyes on the Prize: Tracking Electron Transfer in G-Rich Duplex and Quadruplex DNA Using Enantiopure Ruthenium Polypyridyl Infrared Redox Probes. Journal of the American Chemical Society 2025 147 (33), 29801-29814. DOI: 10.1021/jacs.5c05736
• Kloz, M.; Dostál, J.; Mukherjee, A.; Pižl, M.; Šebesta, F.; Hill, M. G.; Gray, H. B.; Záliš, S.; Vlček, A., Real-Time Tracking of Photoinduced Metal–Metal Bond Formation in a d8d8 Di-Iridium Complex by Vibrational Coherence and Femtosecond Stimulated Raman Spectroscopy. Journal of the American Chemical Society 2025, 147 (11), 9810-9824. DOI: 10.1021/jacs.4c18527
• Sumner, E.; Pižl, M.; McQuaid, K. T.; Hartl, F., Nitrile Substituents at the Conjugated Dipyridophenazine Moiety as Infrared Redox Markers in Electrochemically Reduced Heteroleptic Ru(II) Polypyridyl Complexes. Inorganic Chemistry 2024, 63 (5), 2460-2469. DOI: 10.1021/acs.inorgchem.3c03484
• Kearney, L.; Brandon, M. P.; Coleman, A.; Chippindale, A. M.; Hartl, F.; Lalrempuia, R.; Pižl, M.; Pryce, M. T., Ligand-Structure Effects on N-Heterocyclic Carbene Rhenium Photo- and Electrocatalysts of CO₂ Reduction. Molecules 2023, 28 (10), 4149. DOI: 10.3390/molecules28104149
• Pižl, M.; Hunter, B. M.; Sazanovich, I. V.; Towrie, M.; Gray, H. B.; Záliš, S.; Vlček, A., Excitation-Wavelength-Dependent Photophysics of d8d8 Di-isocyanide Complexes. Inorganic Chemistry 2022, 61 (6), 2745-2759. DOI: 10.1021/acs.inorgchem.1c02645
• Taylor, J. O.; Pižl, M.; Kloz, M.; Rebarz, M.; McCusker, C. E.; McCusker, J. K.; Záliš, S.; Hartl, F.; Vlček, A., Optical and Infrared Spectroelectrochemical Studies of CN-Substituted Bipyridyl Complexes of Ruthenium(II). Inorganic Chemistry 2021, 60 (6), 3514-3523. DOI: 10.1021/acs.inorgchem.0c03579
• Sondermann, C.; Pižl, M.; Paretzki, A.; Feil, C.; Ringenberg, M. R.; Záliš, S.; Kaim, W., Analysis of a Diimine-Organonickel Redox Series. European Journal  of Inorganic Chemistry 2020, 2020 (31), 3010-3015. DOI: 10.1002/ejic.202000455
• Pižl, M.; Picchiotti, A.; Rebarz, M.; Lenngren, N.; Yingliang, L.; Záliš, S.; Kloz, M.; Vlček, A., Time-Resolved Femtosecond Stimulated Raman Spectra and DFT Anharmonic Vibrational Analysis of an Electronically Excited Rhenium Photosensitizer. The Journal of Physical Chemistry A 2020, 124 (7), 1253-1265. DOI: 10.1021/acs.jpca.9b10840
• Guricová, M.; Tobrman, T.; Pižl, M.; Žižková, S.; Hoskovcová, I.; Dvořák, D., Synthesis, characterisation and electrochemical properties of Cr(0) aminocarbene complexes containing condensed heteroaromatic moiety. Journal of  Organometallic Chemistry 2020, 905, 121023. DOI: 10.1016/j.jorganchem.2019.121023